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Premenstrual syndrome - Highlights

Description

An in-depth report on the causes, diagnosis, treatment, and prevention of premenstrual syndrome (PMS).

Alternative Names

PMS

Highlights:

Premenstrual Syndrome Symptoms

Premenstrual syndrome (PMS) can produce physical and emotional or behavioral symptoms.

Physical symptoms of PMS may include:

  • Breast engorgement and tenderness
  • Abdominal bloating
  • Constipation or diarrhea
  • Headache and migraine
  • Swelling of the hands or feet
  • Weight gain
  • Clumsiness
  • Nausea and vomiting
  • Muscle and joint aches or pains

Emotional and behavioral symptoms of PMS may include:

  • Depression (severe depression before menstruation, called premenstrual dysphoric disorder, occurs in about 5% of women with PMS)
  • Anxiety and panic attacks
  • Insomnia
  • Change in sexual interest and desire
  • Irritability
  • Hostility and outbursts of anger
  • Increased appetite often with specific food cravings (especially salt and sugar)
  • Mood swings
  • Inability to concentrate
  • Lethargy and fatigue

Premenstrual Dysphoric Disorder

Premenstrual dysphoric disorder (PMDD) is a specific psychiatric condition marked by severe depression, irritability, and tension before menstruation. For a doctor to confirm a diagnosis of PMDD, the patient must have symptoms during the last week of the premenstrual phase and that resolve within a few days after menstruation starts.

Five or more of the following symptoms must occur:

  • Feeling of sadness or hopelessness, possible suicidal thoughts
  • Feelings of tension or anxiety (panic attacks, in fact, may be much more common in patients with PMDD than in the general population)
  • Mood swings marked by periods of teariness
  • Persistent irritability or anger that affects other people
  • Disinterest in daily activities and relationships
  • Trouble concentrating
  • Fatigue or low energy
  • Food cravings or bingeing
  • Sleep disturbances
  • Feeling out of control
  • Physical symptoms, such as bloating, breast tenderness, headaches, and joint or muscle pain

Resources

References

Braverman PK. Premenstrual syndrome and premenstrual dysphoric disorder. J Pediatr Adolesc Gynecol. 2007 Feb;20(1):3-12.

Brown J, O' Brien PM, Marjoribanks J, Wyatt K. Selective serotonin reuptake inhibitors for premenstrual syndrome. Cochrane Database Syst Rev. 2009 Apr 15;(2):CD001396.

Jarvis CI, Lynch AM, Morin AK. Management strategies for premenstrual syndrome/premenstrual dysphoric disorder. Ann Pharmacother. 2008 Jul;42(7):967-78. Epub 2008 Jun 17

Kwan I and Onwude JL. Premenstrual syndrome. BMJ Clinical Evidence. Web publication date: 01 May 2007.

Lentz GM. Primary and secondary dysmenorrheal, premenstrual syndrome, and premenstrual dysphoric disorder. Etiology, diagnosis, management. In: Katz VL, Lobo RA, Lentz G, Gershenson D, eds. Comprehensive Gynecology. 5th ed. St. Louis, MO: Mosby; 2007:chap 36.

Lopez LM, Kaptein AA, Helmerhorst FM. Oral contraceptives containing drospirenone for premenstrual syndrome. Cochrane Database Syst Rev. 2009 Apr 15;(2):CD006586.

Yonkers KA, O'Brien PM, Eriksson E. Premenstrual syndrome. Lancet. 2008 Apr 5;371(9619):1200-10.

  • Reviewed last on: 8/4/2009
  • Harvey Simon, MD, Editor-in-Chief, Associate Professor of Medicine, Harvard Medical School; Physician, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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