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Interstitial cystitis (IC) - Overview

Alternative Names

Cystitis - interstitial; IC

Definition of Interstitial cystitis (IC):

Interstitial cystitis is a long-term (chronic) inflammation of the bladder wall.

Causes, incidence, and risk factors:

Interstitial cystitis (IC) is a painful condition due to inflammation of the tissues of the bladder wall. The cause is unknown. The condition is usually diagnosed by ruling out other conditions (such as sexually transmitted disease, bladder cancer, and bladder infections).

IC is frequently misdiagnosed as a urinary tract infection. Patients often go years without a correct diagnosis. On average, there is about a 4-year delay between the time the first symptoms occur and the diagnosis is made.

The condition generally occurs around age 30 to 40, although it has been reported in younger people. Women are 10 times more likely to have IC than men.

  • Reviewed last on: 5/22/2008
  • Scott M. Gilbert, MD, Department of Urology, Columbia-Presbyterian Medical Center, New York, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Hanno PM. Painful Bladder Syndrome/Interstitial Cystitis and Related Disorders. In: Wein AJ. Wein: Campbell-Walsh Urology. 9th ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 74.

Moldwin RM. Rational approaches to the treatment of patients with interstitial cystitis. Urology. 2007;69:73-81.

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