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Pancreatic islet cell tumor - Overview

Alternative Names

Islet cell tumors; Islet of Langerhans tumor; Neuroendocrine tumors

Definition of Pancreatic islet cell tumor:

A pancreatic islet cell tumor is an uncommon tumor of the pancreas that arises from a type of cell called the islet cell in the pancreas.

Causes, incidence, and risk factors:

In the normal pancreas, cells called islet cells produce hormones that regulate a variety of bodily functions, such as blood sugar level and the production of stomach acid.

Tumors that arise from islet cells of the pancreas can also produce a variety of hormones, though some do not.

Although islet cells produce many different hormones, most tumors release only one hormone that leads to specific symptoms. Pancreatic islet cell tumors can be noncancerous (benign) or cancerous (malignant).

Islet cell tumors include:

A family history of multiple endocrine neoplasia, type I (MEN I) is a risk factor for islet cell tumors.

  • Reviewed last on: 3/18/2008
  • Elizabeth H. Holt, MD, PhD, Assistant Professor of Medicine, Section of Endocrinology and Metabolism, Yale University. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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