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Respiratory acidosis - Overview

Alternative Names

Ventilatory failure; Respiratory failure; Acidosis - respiratory

Definition of Respiratory acidosis:

Respiratory acidosis is a condition that occurs when the lungs cannot remove all of the carbon dioxide the body produces. This disrupts the body's acid-base balance. Body fluids become too acidic.

Causes, incidence, and risk factors:

Causes of respiratory acidosis include:

  • Diseases of the airways (such as asthma and chronic obstructive lung disease), which send air into and out of the lungs
  • Diseases of the chest (such as scoliosis) that make the lungs less efficient at filling and emptying
  • Disease of the nerves and muscles that "signal" the lungs to inflate or deflate
  • Drugs (including powerful pain medicines, such as narcotics, and "downers," such as benzodiazepines), especially when combined with alcohol
  • Severe obesity

Chronic respiratory acidosis occurs over a long period of time. This leads to a stable situation, because the kidneys increase chemicals that help restore the body's acid-base balance.

Acute respiratory acidosis is a severe condition in which carbon dioxide builds up very quickly and before the kidneys can return the body to a state of balance.

  • Reviewed last on: 11/12/2007
  • Andrew Schriber, M.D., F.C.C.P., Specialist in Pulmonary, Critical Care, and Sleep Medicine, Virtua Memorial Hospital, Mount Holly, New Jersey. Review provided by VeriMed Healthcare Network.

References

Murray J, Nadel J. Textbook of Respiratory Medicine. 3rd ed. Philadelphia, Pa: WB Saunders; 2000:191-192.

Marx J., Hockberger R, Walls R. Rosen’s Emergency Medicine: Concepts and Clinical Practice. 6th ed. St. Louis, Mo: Mosby; 2005.

Ford MD. Clinical Toxicology. 1st ed. Philadelphia, Pa: WB Saunders; 2001:92.

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