Anisindione (By mouth)

Introduction:

Anisindione (an-is-in-DYE-one)

Treats and prevents blood clots in your blood vessels, lungs, or heart.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to anisindione, or if you are pregnant. You should not use this medicine if you have had recent surgery or a stroke. You should not use this medicine if you have certain heart problems, severe liver disease, kidney disease, vitamin C deficiency, or polyarthritis. You should not use this medicine if you have a condition that may cause uncontrolled bleeding (such as a stomach ulcer, cancer, or vitamin K deficiency).

How to Use This Medicine:

Tablet

  • Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

  • Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.
  • Make sure your doctor knows if you are breastfeeding, or if you have high blood pressure, diabetes, blood disorders, an intestinal disease, or an overactive thyroid gland.
  • Your doctor will need to check your blood or urine at regular visits while you are using this medicine. Be sure to keep all appointments.
  • You may bleed more easily while you are using this medicine. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers. Avoid picking your nose. If you need to blow your nose, blow it gently.
  • Do not stop using this medicine suddenly without asking your doctor. You may need to slowly decrease your dose before stopping it completely.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Blood in your urine or stools.
  • Blurred vision.
  • Coughing up blood.
  • Decrease in how much or how often you urinate.
  • Fever, chills, sore throat, cough, or body aches.
  • Heavy menstrual bleeding, or heavy bleeding from a cut or wound.
  • Nausea, vomiting, loss of appetite, or pain in your upper stomach.
  • Prolonged, painful erection of your penis.
  • Purple discoloration of your toes or the soles of your feet.
  • Unusual bleeding, bruising, or weakness.
  • Yellowing of your skin or the whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

  • Diarrhea.
  • Hair loss.
  • Headache.
  • Mild skin rash or itching.
  • Sore mouth or mouth ulcers.
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