Agalsidase beta (Injection)

Introduction:

Agalsidase Beta (aye-GAL-si-days BAY-ta)

Treats Fabry disease (a lack of an enzyme that helps your body break down and use certain kinds of fat).

Brand Name(s):

Fabrazyme

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have ever had an allergic reaction to agalsidase.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
  • A nurse or other trained health professional will give you this medicine.

If a dose is missed:

  • This medicine needs to be given every two weeks. If you miss an appointment, call your doctor or treatment clinic for instructions.

How to Store and Dispose of This Medicine:

  • If you receive your treatments at a clinic, your medicine will be kept there.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breast feeding, or if you have a history of heart problems.
  • This medicine causes a fever in most patients. Your doctor might give you a medicine (such as Tylenol®) to prevent fever before you receive your treatment.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Chest pain.
  • Fast, or uneven heartbeat.
  • Fever, or chills.
  • Rash.
  • Redness, pain, or swelling where the IV is given.
  • Swelling of your lips or ears.

If you notice these less serious side effects, talk with your doctor:

  • Headache, or dizziness.
  • Loss of color in your skin.
  • Mild nausea or vomiting.
  • Muscle, bone, or joint pain.
  • Stomach pain.
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