Acetic Acid
Pronunciation
(a SEE tik AS id)
U.S. Brand Names
VoSol®
Synonyms
Ethanoic Acid
Generic Available
Yes
Use
Irrigation of the bladder; treatment of superficial bacterial infections of the external auditory canal
Pregnancy Risk Factor
C
Contraindications
Hypersensitivity to acetic acid or any component of the formulation; during transurethral procedures
Warnings/Precautions
Not for internal intake or I.V. infusion; topical use or irrigation use only; use of irrigation in patients with mucosal lesions of urinary bladder may cause irritation; systemic acidosis may result from absorption
Adverse Reactions
<1%: Systemic acidosis, urologic pain, hematuria
Dosage
Irrigation (note dosage of an irrigating solution depends on the capacity or surface area of the structure being irrigated):
For continuous irrigation of the urinary bladder with 0.25% acetic acid irrigation, the rate of administration will approximate the rate of urine flow; usually 500-1500 mL/24 hours
For periodic irrigation of an indwelling urinary catheter to maintain patency, about 50 mL of 0.25% acetic acid irrigation is required
Otic: Insert saturated wick; keep moist 24 hours; remove wick and instill 5 drops 3-4 times/day
Administration
Not for internal intake or I.V. infusion; topical use or irrigation use only
Nursing Implications
For continuous or intermittent irrigation of the urinary bladder, urine pH should be checked at least 4 times/day and the irrigation rate adjusted to maintain a pH of 4.5-5
Dental Health: Effects on Dental Treatment
No significant effects or complications reported
Dental Health: Vasoconstrictor/Local Anesthetic Precautions
No information available to require special precautions
Mental Health: Effects on Mental Status
None reported
Mental Health: Effects on Psychiatric Treatment
None reported
Dosage Forms
Solution for irrigation: 0.25% (250 mL, 500 mL, 1000 mL)
Solution, otic (V
Sol®): 2% [in propylene glycol] (15 mL)
References
Kawamata M, Fujita S, and Mayumi T, "Acetic Acid Intoxication by Rectal Administration,"
J Toxicol Clin Toxicol
, 1994, 32(3):333-6.
Penner GE, "Acid Ingestion: Toxicology and Treatment,"
Ann Emerg Med
, 1980, 9(7):374-9.
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